• AIS E – Normal
    • Sensory and motor function are normal
  •  

    Determining the Neurological Level of Injury (NLI)

    The NLI is defined as the lowest level where both sensory and motor function are intact.

    This is not always the same as:

    Understanding this distinction is essential when communicating prognosis and planning treatment.  

    What is a Zone of Partial Preservation (ZPP)?

    The Zone of Partial Preservation (ZPP) is a classification which was historically used only in complete spinal cord injuries (AIS A) to describe how far below the neurological level some function still exists.

    In other words, even when an injury is classified as “complete,” there may still be some preserved sensory or motor function below the level of injury—just not all the way to the sacral segments (S4–S5).

    However, newer guidance allows ZPP to be applied in select incomplete injuries under specific conditions, allowing for further description of how much function exists below the NLI without a change to the AIS classification.

    ZPP identifies the lowest spinal segments with any preserved function:

    This should be documented separately for the right vs. left side.

    Patients with more extensive ZPP:

    This can also help guide treatment focus, as preserved motor zones may be targets for NMES/FES to drive muscle re-education and strengthening. Preserved sensory zones may support improved body awareness during functional mobility.

    Why the AIS Matters Clinically

    1. Prognosis

    It is important to remember that the AIS grade can change with time and rehabilitation, which is why reassessment of the AIS is recommended at various intervals and as presentation evolves. AIS classification is strongly associated with recovery potential:

    While not absolute, these trends are useful for setting expectations early on.

    2. Goal Setting

    When writing goals, the AIS score can help guide realistic, individualized goals:

    3. Treatment Planning

    AIS classification can influence intervention selection, below is by no means an exhaustive list of treatments, but a few to consider:

    For individuals with AIS A or B and sufficient upper body and core strength, KAFO training may be appropriate

    How to Use AIS in Everyday Practice

    Instead of viewing AIS as a one-time classification, think of it as a clinical anchor point:

    Limitations of the ASIA Impairment Scale

    While AIS is widely used in SCI rehabilitation, it has important limitations to consider in clinical practice.

    1. It Measures Impairment—Not Function

    AIS reflects neurological impairment, not overall function. Individuals with the same AIS grade can have very different levels of independence and abilities.

    2. It Does Not Capture the Full Clinical Picture

    The ASIA exam focuses on sensory and motor function, but does not account for factors like pain, spasticity, or dysesthesias, all of which can significantly impact outcomes.

    3. It Depends on the Exam

    Classification is based on a bedside assessment and can be influenced by patient presentation and examiner experience. Subtle findings, particularly sacral sparing, can affect grading if not assessed carefully.

    4. It Simplifies a Complex Injury

    AIS groups injuries into broad categories, which may not fully reflect differences in preserved function between individuals. Additional details, like the ZPP, help provide a more complete picture.

    5. It Represents a Point in Time

    AIS reflects a single moment in recovery and can change, especially early after injury. Some individuals initially classified as complete may later demonstrate features of incomplete injury.

    AIS is a valuable framework for classifying spinal cord injury, but it should not be used in isolation.

    It is best understood as:

    Putting It All Together

    The ASIA Impairment Scale gives clinicians a shared language to describe SCI severity. But its real value comes from how it informs decision-making:

    Combined with functional outcome measures and clinical reasoning, AIS helps guide rehabilitation priorities and progression, but it does not define the individual or limit what may be possible over time.

    References

     

    Determining the Neurological Level of Injury (NLI)

    The NLI is defined as the lowest level where both sensory and motor function are intact.

    This is not always the same as:

    Understanding this distinction is essential when communicating prognosis and planning treatment.  

    What is a Zone of Partial Preservation (ZPP)?

    The Zone of Partial Preservation (ZPP) is a classification which was historically used only in complete spinal cord injuries (AIS A) to describe how far below the neurological level some function still exists.

    In other words, even when an injury is classified as “complete,” there may still be some preserved sensory or motor function below the level of injury—just not all the way to the sacral segments (S4–S5).

    However, newer guidance allows ZPP to be applied in select incomplete injuries under specific conditions, allowing for further description of how much function exists below the NLI without a change to the AIS classification.

    ZPP identifies the lowest spinal segments with any preserved function:

    This should be documented separately for the right vs. left side.

    Patients with more extensive ZPP:

    This can also help guide treatment focus, as preserved motor zones may be targets for NMES/FES to drive muscle re-education and strengthening. Preserved sensory zones may support improved body awareness during functional mobility.

    Why the AIS Matters Clinically

    1. Prognosis

    It is important to remember that the AIS grade can change with time and rehabilitation, which is why reassessment of the AIS is recommended at various intervals and as presentation evolves. AIS classification is strongly associated with recovery potential:

    While not absolute, these trends are useful for setting expectations early on.

    2. Goal Setting

    When writing goals, the AIS score can help guide realistic, individualized goals:

    3. Treatment Planning

    AIS classification can influence intervention selection, below is by no means an exhaustive list of treatments, but a few to consider:

    For individuals with AIS A or B and sufficient upper body and core strength, KAFO training may be appropriate

    How to Use AIS in Everyday Practice

    Instead of viewing AIS as a one-time classification, think of it as a clinical anchor point:

    Limitations of the ASIA Impairment Scale

    While AIS is widely used in SCI rehabilitation, it has important limitations to consider in clinical practice.

    1. It Measures Impairment—Not Function

    AIS reflects neurological impairment, not overall function. Individuals with the same AIS grade can have very different levels of independence and abilities.

    2. It Does Not Capture the Full Clinical Picture

    The ASIA exam focuses on sensory and motor function, but does not account for factors like pain, spasticity, or dysesthesias, all of which can significantly impact outcomes.

    3. It Depends on the Exam

    Classification is based on a bedside assessment and can be influenced by patient presentation and examiner experience. Subtle findings, particularly sacral sparing, can affect grading if not assessed carefully.

    4. It Simplifies a Complex Injury

    AIS groups injuries into broad categories, which may not fully reflect differences in preserved function between individuals. Additional details, like the ZPP, help provide a more complete picture.

    5. It Represents a Point in Time

    AIS reflects a single moment in recovery and can change, especially early after injury. Some individuals initially classified as complete may later demonstrate features of incomplete injury.

    AIS is a valuable framework for classifying spinal cord injury, but it should not be used in isolation.

    It is best understood as:

    Putting It All Together

    The ASIA Impairment Scale gives clinicians a shared language to describe SCI severity. But its real value comes from how it informs decision-making:

    Combined with functional outcome measures and clinical reasoning, AIS helps guide rehabilitation priorities and progression, but it does not define the individual or limit what may be possible over time.

    References

    The ASIA Impairment Scale (AIS) is an essential classification system in spinal cord injury (SCI) rehabilitation. This guide breaks down what the AIS is, how the test is carried out and what the scores mean, and—most importantly—how to use it to guide treatment and set expectations.

    What is the ASIA Impairment Scale?

    The ASIA Impairment Scale is part of the International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI). It provides a standardized way to classify the severity and completeness of a spinal cord injury based on a detailed sensory and motor exam.

    This exam is typically completed within 72 hours of injury, upon admission to inpatient rehabilitation, at discharge, and then at the one-year mark, however this frequency may be adjusted depending on various factors.

    Key Components of the ASIA Exam

    1. Sensory Testing

    Tested across 28 dermatomes bilaterally

    Diagram of the human body showing key sensory points for the ASIA Impairment Scale exam, including labeled dermatomes from C2 through S4–5 on the face, neck, torso, arms, hands, legs, feet, and sacral region.

    2. Motor Testing

    5= Full ROM against gravity with full resistance

    3. Sacral Sparing

    Sacral sparing refers to the preservation of any sensory or motor function in the lowest sacral segments of the spinal cord (S4–S5) following SCI.

    These segments correspond to:

    Even minimal function here changes the entire classification of the injury because the presence of sacral sparing automatically designates an injury as incomplete. If sacral sparing is absent, the injury is classified as complete (AIS A).

    How Sacral Sparing is Assessed

    There are three key components, and documenting any one of them counts as sacral sparing:

    1. Light Touch or Pinprick at S4–S5

    Clinical note: This can sometimes be present even when sensation is absent in more proximal dermatomes.

    2. Deep Anal Pressure (DAP)

    Key point: DAP is often preserved even when light touch/pinprick are absent, making it especially important in borderline cases.

    3. Voluntary Anal Contraction (VAC)

    This is the only motor component of sacral sparing.

    ASIA Impairment Scale/AIS Grade

    Based on the exam detailed above, a patient will be given a grade A-E, as detailed below:

     

    Determining the Neurological Level of Injury (NLI)

    The NLI is defined as the lowest level where both sensory and motor function are intact.

    This is not always the same as:

    Understanding this distinction is essential when communicating prognosis and planning treatment.  

    What is a Zone of Partial Preservation (ZPP)?

    The Zone of Partial Preservation (ZPP) is a classification which was historically used only in complete spinal cord injuries (AIS A) to describe how far below the neurological level some function still exists.

    In other words, even when an injury is classified as “complete,” there may still be some preserved sensory or motor function below the level of injury—just not all the way to the sacral segments (S4–S5).

    However, newer guidance allows ZPP to be applied in select incomplete injuries under specific conditions, allowing for further description of how much function exists below the NLI without a change to the AIS classification.

    ZPP identifies the lowest spinal segments with any preserved function:

    This should be documented separately for the right vs. left side.

    Patients with more extensive ZPP:

    This can also help guide treatment focus, as preserved motor zones may be targets for NMES/FES to drive muscle re-education and strengthening. Preserved sensory zones may support improved body awareness during functional mobility.

    Why the AIS Matters Clinically

    1. Prognosis

    It is important to remember that the AIS grade can change with time and rehabilitation, which is why reassessment of the AIS is recommended at various intervals and as presentation evolves. AIS classification is strongly associated with recovery potential:

    While not absolute, these trends are useful for setting expectations early on.

    2. Goal Setting

    When writing goals, the AIS score can help guide realistic, individualized goals:

    3. Treatment Planning

    AIS classification can influence intervention selection, below is by no means an exhaustive list of treatments, but a few to consider:

    For individuals with AIS A or B and sufficient upper body and core strength, KAFO training may be appropriate

    How to Use AIS in Everyday Practice

    Instead of viewing AIS as a one-time classification, think of it as a clinical anchor point:

    Limitations of the ASIA Impairment Scale

    While AIS is widely used in SCI rehabilitation, it has important limitations to consider in clinical practice.

    1. It Measures Impairment—Not Function

    AIS reflects neurological impairment, not overall function. Individuals with the same AIS grade can have very different levels of independence and abilities.

    2. It Does Not Capture the Full Clinical Picture

    The ASIA exam focuses on sensory and motor function, but does not account for factors like pain, spasticity, or dysesthesias, all of which can significantly impact outcomes.

    3. It Depends on the Exam

    Classification is based on a bedside assessment and can be influenced by patient presentation and examiner experience. Subtle findings, particularly sacral sparing, can affect grading if not assessed carefully.

    4. It Simplifies a Complex Injury

    AIS groups injuries into broad categories, which may not fully reflect differences in preserved function between individuals. Additional details, like the ZPP, help provide a more complete picture.

    5. It Represents a Point in Time

    AIS reflects a single moment in recovery and can change, especially early after injury. Some individuals initially classified as complete may later demonstrate features of incomplete injury.

    AIS is a valuable framework for classifying spinal cord injury, but it should not be used in isolation.

    It is best understood as:

    Putting It All Together

    The ASIA Impairment Scale gives clinicians a shared language to describe SCI severity. But its real value comes from how it informs decision-making:

    Combined with functional outcome measures and clinical reasoning, AIS helps guide rehabilitation priorities and progression, but it does not define the individual or limit what may be possible over time.

    References